Department of Pharmaceutical Technology

Department of Pharmaceutical Technology (General Description)

Pharmaceutical Technology can be briefly summarized as all technologies related to the development of a pharmaceutical form using natural, semi-synthetic and synthetic active and auxiliary substances, production in industry and use in patients. Performs necessary analysis, test and quality control studies in these stages and develops new analysis and test methods if necessary.

In order to teach these subjects, theoretical courses and laboratories of Pharmaceutical Technology I-II-III-IV, Cosmetology, Biopharmaceutical, Pharmacokinetics, 5th year courses and 5 Pharmacy Technician courses are given in Atatürk Vocational School.

With our laboratories equipped with the latest technology, scientific infrastructure and research facilities, scientists are trained.

Within the scope of the vocational training programs that we carry out as a requirement of lifelong education, besides the trainings such as cosmetic products, majistral preparations for manufacturers and pharmacists, training in advanced Pharmaceutical Technology, production, GMP and licensing for all graduates and industry is also included.

In this period, more than ten TÜBİTAK (1001-1003-1002-1505) projects and 14 BAP (Scientific Research Project) projects are carried out in our department.

It prepares magistral medication in line with the daily prescriptions from the surrounding hospitals.

All kinds of cosmetic and pharmaceutical products are developed in our laboratories and various services including analysis and quality controls are offered. The interactions of formulations with active substances, development of new drug delivery systems, release studies in the formulations as well as finished product stability studies and physicochemical analyzes are performed within the scope of Revolving Fund Services.

Research Areas

Tablets, capsules (solid drug forms)
Parenteral dosage forms and parenteral drug production
Ointment, cream, emulsion, gel (semi-solid drug forms),
Microparticle, microsponge
Nano-particulate formulations (polymeric and lipidic nanoparticles, liposomes)
Patches
Studies on drug production and testing methods
Development of new formulations of cosmetics
Testing of cosmetic products and safety assessment studies
Correlation of in vitro methods with in vivo results
Accelerated stability studies of improved drug formulations

UNDERGRADUATE EDUCATION

Pharmaceutical Technology I (5th semester)

Aim and goal

The aim of this course is to teach the definitions of drugs and raw materials used in preparation of dosage forms, research on classical and modern therapeutic formulations, preparation of drugs by extraction methods, packaging materials and the interaction of dyes with these materials.

Course contents

Pharmaceutical, heating, mixing and filtration methods
Water
Solutions
Extraction methods and drugs prepared by extraction methods
Aerosols
Storage of packaging materials and packaged medicines
Dyestuffs

Pharmaceutical Technology II (6th semester)

Aim and goal

The aim of the course is to provide the students with the knowledge about the structure and preparation and application of two-phase, colloidal, semi-solid drug systems and suppositories.

Course contents

Colloids
Suspensions
Emulsions
Ointments
Pastes
Suppositories

Pharmaceutical Technology III (7th semester)

Aim and goal

Throughout the pharmaceutical technology course, students will learn about isotonic formulation. It includes information and technology on sterilization and contamination prevention, drug stability and incompatibility.

Course contents

Isotonic solutions
Sterilization methods
Contamination
Drug stability
Incompatibilities
Surgical materials

Pharmaceutical Technology IV (8th semester)

Aim and goal

In this course, students learn about the classical and modern therapeutic formulations of solid dosage forms such as controlled release systems, powders, capsules and tablets. In this course, natural, semi-synthetic and synthetic materials (auxiliary materials) used in the preparations, preparation and application methods, technologies, quality control studies, stability and incompatibility of drugs are given.

Course contents

Gelatin capsules
Granular
Tablets
Controlled release systems

In practical studies; In the laboratory, students are required to prepare dosage forms related to the subjects in Pharmaceutical Technology courses.

Good Manufacturing Practices in Pharmaceuticals (9th semester)

Aim and goal

Gaining the industrial knowledge and experience required in the production processes of pharmaceutical active compounds and pharmaceutical forms in the pharmaceutical industry. In this context, in the framework of good production practices, synthetic, semisynthetic and biological active substance production techniques, radiopharmaceutical production applications and pharmaceutical shape production technologies are introduced and related to national and international criteria in this field are explained with good production practices and licensing stages.

Course Contents

Introduction of good manufacturing practices and good manufacturing practice guidelines
Introduction of the common technical document file quality module and its relationship with good production practices
Production of active substances
Synthetic and semi-synthetic production techniques
Considerations and limitations in the production of synthetic active substances according to the International Conference on Harmonization (ICH) and European Medicines Agency (EMEA) criteria
Biological production techniques
Biotechnological production techniques
Methods for increasing productivity in recombinant drug production
Microbiological production techniques
Production and quality control of immunological products
Production of antibiotics and fermentation techniques
Microbial origin products used in treatment
General sterilization and hygiene approach in production
Plant production techniques
Basic principles of medicinal plant culture
Basic principles of drug preparation
Cell suspension and tissue culture method
Herbal medicine production standards
Pharmaceutical shape production
Pharmaceutical production techniques
Pharmaceutical engineering
Quality design
New pharmaceutical form production techniques
Extrusion techniques
Peptide-protein formulation
Nanoparticles
Multiparticular systems
Gums
Radiopharmaceutical production techniques
Good radiopharmaceutical applications
Radionuclide and radiopharmaceutical production and EMEA criteria
Dosage forms and preparations of radiopharmaceuticals in pharmacopoeias