EGE UNIVERSITY

Faculty of Pharmacy

Department of Pharmaceutical Technology

Department of Pharmaceutical Technology (General Description)

Pharmaceutical Technology can be briefly summarized as all technologies related to the development of a pharmaceutical form using natural, semi-synthetic and synthetic active and auxiliary substances, production in industry and use in patients. Performs necessary analysis, test and quality control studies in these stages and develops new analysis and test methods if necessary.

In order to teach these subjects, theoretical courses and laboratories of Pharmaceutical Technology I-II-III-IV, Cosmetology, Biopharmaceutical, Pharmacokinetics, 5th year courses and 5 Pharmacy Technician courses are given in Atatürk Vocational School.

With our laboratories equipped with the latest technology, scientific infrastructure and research facilities, scientists are trained.

Within the scope of the vocational training programs that we carry out as a requirement of lifelong education, besides the trainings such as cosmetic products, majistral preparations for manufacturers and pharmacists, training in advanced Pharmaceutical Technology, production, GMP and licensing for all graduates and industry is also included.

In this period, more than ten TÜBİTAK (1001-1003-1002-1505) projects and 14 BAP (Scientific Research Project) projects are carried out in our department.

It prepares magistral medication in line with the daily prescriptions from the surrounding hospitals.

All kinds of cosmetic and pharmaceutical products are developed in our laboratories and various services including analysis and quality controls are offered. The interactions of formulations with active substances, development of new drug delivery systems, release studies in the formulations as well as finished product stability studies and physicochemical analyzes are performed within the scope of Revolving Fund Services.

Research Areas

  • Tablets, capsules (solid drug forms)
  • Parenteral dosage forms and parenteral drug production
  • Ointment, cream, emulsion, gel (semi-solid drug forms),
  • Microparticle, microsponge
  • Nano-particulate formulations (polymeric and lipidic nanoparticles, liposomes)
  • Patches
  • Studies on drug production and testing methods
  • Development of new formulations of cosmetics
  • Testing of cosmetic products and safety assessment studies
  • Correlation of in vitro methods with in vivo results
  • Accelerated stability studies of improved drug formulations

UNDERGRADUATE EDUCATION

Pharmaceutical Technology I (5th semester)

Aim and goal

The aim of this course is to teach the definitions of drugs and raw materials used in preparation of dosage forms, research on classical and modern therapeutic formulations, preparation of drugs by extraction methods, packaging materials and the interaction of dyes with these materials.

Course contents

  • Pharmaceutical, heating, mixing and filtration methods
  • Water
  • Solutions
  • Extraction methods and drugs prepared by extraction methods
  • Aerosols
  • Storage of packaging materials and packaged medicines
  • Dyestuffs

Pharmaceutical Technology II (6th semester)

Aim and goal

The aim of the course is to provide the students with the knowledge about the structure and preparation and application of two-phase, colloidal, semi-solid drug systems and suppositories.

Course contents

  • Colloids
  • Suspensions
  • Emulsions
  • Ointments
  • Pastes
  • Suppositories

Pharmaceutical Technology III (7th semester)

Aim and goal

Throughout the pharmaceutical technology course, students will learn about isotonic formulation. It includes information and technology on sterilization and contamination prevention, drug stability and incompatibility.

Course contents

  • Isotonic solutions
  • Sterilization methods
  • Contamination
  • Drug stability
  • Incompatibilities
  • Surgical materials

Pharmaceutical Technology IV (8th semester)

Aim and goal

In this course, students learn about the classical and modern therapeutic formulations of solid dosage forms such as controlled release systems, powders, capsules and tablets. In this course, natural, semi-synthetic and synthetic materials (auxiliary materials) used in the preparations, preparation and application methods, technologies, quality control studies, stability and incompatibility of drugs are given.

Course contents

  • Gelatin capsules
  • Granular
  • Tablets
  • Controlled release systems

In practical studies; In the laboratory, students are required to prepare dosage forms related to the subjects in Pharmaceutical Technology courses.

Good Manufacturing Practices in Pharmaceuticals (9th semester)

Aim and goal

Gaining the industrial knowledge and experience required in the production processes of pharmaceutical active compounds and pharmaceutical forms in the pharmaceutical industry. In this context, in the framework of good production practices, synthetic, semisynthetic and biological active substance production techniques, radiopharmaceutical production applications and pharmaceutical shape production technologies are introduced and related to national and international criteria in this field are explained with good production practices and licensing stages.

Course Contents

  • Introduction of good manufacturing practices and good manufacturing practice guidelines
  • Introduction of the common technical document file quality module and its relationship with good production practices
  • Production of active substances
  • Synthetic and semi-synthetic production techniques
  • Considerations and limitations in the production of synthetic active substances according to the International Conference on Harmonization (ICH) and European Medicines Agency (EMEA) criteria
  • Biological production techniques
  • Biotechnological production techniques
  • Methods for increasing productivity in recombinant drug production
  • Microbiological production techniques
  • Production and quality control of immunological products
  • Production of antibiotics and fermentation techniques
  • Microbial origin products used in treatment
  • General sterilization and hygiene approach in production
  • Plant production techniques
  • Basic principles of medicinal plant culture
  • Basic principles of drug preparation
  • Cell suspension and tissue culture method
  • Herbal medicine production standards
  • Pharmaceutical shape production
  • Pharmaceutical production techniques
  • Pharmaceutical engineering
  • Quality design
  • New pharmaceutical form production techniques
  • Extrusion techniques
  • Peptide-protein formulation
  • Nanoparticles
  • Multiparticular systems
  • Gums
  • Radiopharmaceutical production techniques
  • Good radiopharmaceutical applications
  • Radionuclide and radiopharmaceutical production and EMEA criteria
  • Dosage forms and preparations of radiopharmaceuticals in pharmacopoeias

 

Farmasötik Teknoloji Anabilim Dalı Öğretim Üyeleri

Prof. Dr. Levent KIRILMAZ

Prof. Dr. Özgen ÖZER (A. D. Başkanı)

Prof . Dr. Esra BALOĞLU

Prof. Dr. Yeşim KARASULU

Prof. Dr. Ercüment KARASULU

Prof. Dr. Işık ÖZGÜNEY

Prof. Dr. Mine ÖZYAZICI

Doç. Assos. Prof. Dr. Sinem Yaprak KARAVANA

Assoc. Prof. Dr. Evren Homan GÖKÇE

Assoc. Prof. Dr. Mesut ARICI

Assoc. Prof. Dr. Emel Öykü ÇETİN UYANIKGİL

Assoc Prof. Dr. Sakine TUNCAY TANRIVERDİ

Res. Asst. Dr. Aysu YURDASİPER

Res. Asst. Dr. Gülbeyaz YILDIZ

Res. Asst. Dr. Seda RENÇBER

Res. Asst. Dr. Erkan AZİZOĞLU

Res. Asst. Gülçin ARSLAN AZİZOĞLU

Dr. Mehmet Ali EGE